3-Iodo-4-fluorobenzoic acid
4-Fluoro-3-iodobenzoic acid
CAS: 403-18-9
Molecular Formula: C7H4FIO2
3-Iodo-4-fluorobenzoic acid - Names and Identifiers
| Name | 4-Fluoro-3-iodobenzoic acid |
| Synonyms | BUTTPARK 122 1-04 4-Fluoro-3-iodobenzoic acid 4-FLUORO-3-IODOBENZOIC ACID 3-Iodo-4-fluorobenzoic acid Benzoic acid, 4-fluoro-3-iodo- |
| CAS | 403-18-9 |
3-Iodo-4-fluorobenzoic acid - Physico-chemical Properties
| Molecular Formula | C7H4FIO2 |
| Molar Mass | 266.01 |
| Density | 2.074 |
| Melting Point | 176.6-177 |
| Boling Point | 339℃ |
| Flash Point | 159℃ |
| pKa | 3.79±0.10(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Sensitive | Light Sensitive |
| MDL | MFCD03788556 |
3-Iodo-4-fluorobenzoic acid - Risk and Safety
| Risk Codes | 25 - Toxic if swallowed |
| Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| Hazard Note | Irritant |
3-Iodo-4-fluorobenzoic acid - Introduction
4-Fluoro-3-iodobenzoic acid(4-Fluoro-3-iodobenzoic acid) is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 4-Fluoro-3-iodobenzoic acid is a white crystalline solid.
-Solubility: It is soluble in organic solvents such as ethanol, dimethyl sulfide and chloroform at room temperature, but insoluble in water.
Use:
-Chemical synthesis: 4-Fluoro-3-iodobenzoic acid is often used as a raw material or intermediate in organic synthesis for the synthesis of other compounds. It can participate in coupling reactions, carboxylic acid esterification reactions, aromatic electrophilic substitution reactions, etc.
-Drug synthesis: Due to its special structure, it can be used in the field of drug research and drug synthesis.
Preparation Method:
4-Fluoro-3-iodobenzoic acid can be synthesized by the following steps:
1. 4-Fluoro-3-iodobenzoic acid is obtained by reacting 4-fluorobenzoic acid with iodide.
Safety Information:
- 4-Fluoro-3-iodobenzoic acid has low toxicity and rarely harms the human body under normal operating conditions.
-However, any chemical substances need to be handled with care. When using or handling the compound, care should be taken to prevent inhalation of gases, contact with skin and eyes.
-When handling 4-Fluoro-3-iodobenzoic acid, wear appropriate protective equipment such as lab gloves, safety glasses, and lab coats to ensure personal safety. At the same time, it should also be operated in a well-ventilated place.
Nature:
-Appearance: 4-Fluoro-3-iodobenzoic acid is a white crystalline solid.
-Solubility: It is soluble in organic solvents such as ethanol, dimethyl sulfide and chloroform at room temperature, but insoluble in water.
Use:
-Chemical synthesis: 4-Fluoro-3-iodobenzoic acid is often used as a raw material or intermediate in organic synthesis for the synthesis of other compounds. It can participate in coupling reactions, carboxylic acid esterification reactions, aromatic electrophilic substitution reactions, etc.
-Drug synthesis: Due to its special structure, it can be used in the field of drug research and drug synthesis.
Preparation Method:
4-Fluoro-3-iodobenzoic acid can be synthesized by the following steps:
1. 4-Fluoro-3-iodobenzoic acid is obtained by reacting 4-fluorobenzoic acid with iodide.
Safety Information:
- 4-Fluoro-3-iodobenzoic acid has low toxicity and rarely harms the human body under normal operating conditions.
-However, any chemical substances need to be handled with care. When using or handling the compound, care should be taken to prevent inhalation of gases, contact with skin and eyes.
-When handling 4-Fluoro-3-iodobenzoic acid, wear appropriate protective equipment such as lab gloves, safety glasses, and lab coats to ensure personal safety. At the same time, it should also be operated in a well-ventilated place.
Last Update：2024-04-09 21:11:58
